Olfactory function in patients with nonsyndromic orofacial clefts and their unaffected relatives
نویسندگان
چکیده
منابع مشابه
Three-dimensional morphometric analysis of craniofacial shape in the unaffected relatives of individuals with nonsyndromic orofacial clefts: a possible marker for genetic susceptibility.
Numerous studies have described altered patterns of craniofacial form in the unaffected relatives of individuals with nonsyndromic clefts. Unfortunately, results from such studies have been highly variable and have failed to provide a reliable method for differentiating "at-risk" relatives from controls. In the present study, we compared craniofacial shape between a sample of unaffected relativ...
متن کاملGenetics and genomics etiology of nonsyndromic orofacial clefts
Orofacial clefts (OFC) are complex birth defects. Studies using contemporary genomic techniques, bioinformatics, and statistical analyses have led to appreciable advances in identifying the causes of syndromic forms of clefts. This commentary gives an overview of the important cleft gene discoveries found using various genomic methods and tools.
متن کاملExecutive functioning in anorexia nervosa patients and their unaffected relatives.
Formal genetic studies suggested a substantial genetic influence for anorexia nervosa (AN), but currently results are inconsistent. The use of the neurocognitive endophenotype approach may facilitate our understanding of the AN pathophysiology. We investigated decision-making, set-shifting and planning in AN patients (n=29) and their unaffected relatives (n=29) compared to healthy probands (n=2...
متن کاملAssociation between PAX7 and NTN1 gene polymorphisms and nonsyndromic orofacial clefts in a northern Chinese population
BACKGROUND Nonsyndromic orofacial clefts (NSOC) are the most common orofacial congenital defect with a complex etiology. Genome-wide association studies have identified paired box protein 7 (PAX7) and netrin-1 (NTN1) as candidate susceptibility genes for NSOC in both European and Asian populations. Here, possible associations between single-nucleotide polymorphisms (SNPs) in or near PAX7 and NT...
متن کاملAbstract P10. Enteral Feeding Access in Patients with Orofacial Clefts
METHODS: Patients with completed breast reconstructions of all types from 2009–2011 completed BreastQ questionnaires. Postoperative photos were graded by a six member panel using a breast reconstruction-specific aesthetic scale. Scores from the BreastQ domain “satisfaction with breasts” (BrSat) were compared with the photo-based grades (PhotoGr). Patients were categorized: Group 1, BrSat >Photo...
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ژورنال
عنوان ژورنال: American Journal of Medical Genetics Part A
سال: 2018
ISSN: 1552-4825
DOI: 10.1002/ajmg.a.40348